GW501516is a drug that was produced by GlaxoWellcome (yes, GW stands for the name of the company that pioneered in its development). It is known for many other names, but it has become widely popular because of its endurance-enhancing aspect. Due to the fact that it is an agonist of the receptor of the PPAR-delta, further studies for the development of the drug have been abandoned. Therefore, at present, it is declared as an illegal drug used in conjunction with sports.
In the past, the drug began to lose its reputation when the WADA publicly aired its warning against the GW501516. The warning came out in March 2013 and it basically shares the risks that it may present to the health of the people who will use it. The warning was actually just a result of a new set of data on the safety of the drug. For quite some time, there have been doubts in connection with the safety of the drug. However, no clear warnings were given, hence making it technically legal to market the drug as a supplement for training of a person’s endurance. In fact, the drug is called as the Endurobol in the market. It gives a notion that this is the “positive kind of doping.”
The target market of the Endurobol is clearly the athletes and the physically active. Even if there are disclaimers that Endurobol is not meant for the consumption of human beings, having a brand name that sounds like a positive supplement can be misleading. According to experts, the name should not be used. The drug should be sold using its original and more popular name: GW501516, that is.
In the wider society, it is far from possible to ban this drug. Only the athletes who are functioning as professionals are prohibited from using this drug. But the general public should be warned that it is known to modify or drastically change the function of the cells. The information about it is readily available, given that there are at least 200 papers that address issues and concerns about the drug.
In 2004, there was a paper that has concurred with the claim that the drug is potent in reducing obesity level (especially those that are induced by a high level of fat intake). This is the main reason why the drug is so interesting not just for the companies and drug developers, but also to the other members of the society.
So what are the risks of taking in GW501516? For one, there are claims that long term intake of the drug can result to cancer. It may not also work as a long term cure for obesity and related diseases because the body tends to have a certain degree of resistance to the drug. So, in the end, the patient will still get fat. Truth be told, despite the fact that the developer of the drug remains mum on why it stopped the development of the drug, the mere act of halting already tells a lot. In summary, the following are the things that one should remember about GW501516:
- In animal studies, it was found out that indeed, the drug is effective in increasing or improving the level of performance of the subjects investigated (all of which are animals);
- For human beings (adult), the drug is foreseen not to be very effective in enhancing the performance in endurance sports, but it can potentially reduce body fat content;
- There exists no reliable related investigations that will prove that the drug can enhance the performance of athletes; and
- According to studies, the long term use of the drug can be dangerous because it can lead to cancer.
The manufacturers of the drug have always been clear about the fact that the drug was not developed for human consumption. Therefore, it is clear that it will pose health risks on the part of the person who will ingest it. If you are willing to take the risk, proceed. But you have been properly warned.